What percentage of the body's total daily insulin secretion is released basally in a healthy person?

In a healthy individual, basal insulin secretion plays a crucial role in maintaining blood glucose levels throughout the day, particularly during fasting periods between meals and overnight. The body releases insulin in a steady, low concentration to support metabolic processes and prevent excessive fluctuations in blood sugar levels.

Typically, about 50% of the total daily insulin secretion occurs basally. This means that when considering a 24-hour period, half of the insulin produced is secreted continuously to manage glucose levels, while the other half is released in response to food intake (prandial secretion). This balance is essential for effective glucose homeostasis.

Basal insulin secretion ensures that tissues, particularly muscle and fat, remain sensitive to insulin's effects, thereby facilitating the uptake of glucose even when food is not being consumed. Understanding this proportion aids in grasping how the endocrine system regulates metabolism effectively.